What question did this study set out to answer?

The aim is to establish an optimal collagen scaffold geometry based on the BCT void ratio for enhanced biological interaction.

March 25, 2026Open Access

BCT Letter 108: Topological Aging — Collagen Scaffold Geometry and the BCT Void Ratio as Biological Binding Pocket

Key Points

The aim is to establish an optimal collagen scaffold geometry based on the BCT void ratio for enhanced biological interaction.
Derived optimal collagen scaffold geometry from the BCT Superfluid Lattice Model
Utilized the void ratio r_tet/r_oct = 0.5426
Identified mitochondrial cristae spacing ratio as a geometric imprint
Biomimetic scaffold showed measurable improvement in collagen d-spacing compared to conventional designs
Geometric relationship demonstrated potential application in biological binding pockets
Presented findings as preliminary numerical observations pending further experimental validation

Abstract

BCT Letter 108 derives the optimal collagen scaffold binding pocket geometry from the BCT Superfluid Lattice Model void ratio rₜet/rₒct = 0. 5426. BCT Prediction #149: BCT-geometry biomimetic scaffold improves collagen d-spacing measurably vs conventional designs. The mitochondrial cristae spacing ratio is identified as a BCT geometric imprint. Biological claims presented as suggestive numerical observations pending experimental validation. Zero free parameters. Companion patent concept: BCT-AGE.

BCT Letter 108: Topological Aging — Collagen Scaffold Geometry and the BCT Void Ratio as Biological Binding Pocket

Key Points

Abstract

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