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This research investigates the link between renal resistive index and the decline in estimated glomerular filtration rate (eGFR) in patients with IgA nephropathy.

March 28, 2026Open Access

WCN26-4437 ASSOCIATION BETWEEN RENAL RESISTIVE INDEX AND DECLINE IN eGFR IN PATIENTS WITH BIOPSY-PROVEN IgA NEPHROPATHY

Key Points

This research investigates the link between renal resistive index and the decline in estimated glomerular filtration rate (eGFR) in patients with IgA nephropathy.
Conducted a real-world study on patients with biopsy-proven IgA nephropathy.
Administered a low-to medium-dose of telitacicept alongside conventional therapy.
Evaluated eGFR changes and renal resistive index measurements.
Low-to medium-dose telitacicept showed effective onset efficacy.
The combination therapy was well-tolerated and safe for patients.
Improvement in eGFR observed in treated patients.

Abstract

Conclusion:In this real-world study, low-to medium-dose of telitacicept combined with conventional therapy showed good onset efficacy and safety for treating IgA patients.I have no potential conflict of interest to disclose.I did not use generative AI and AI-assisted technologies in the writing process.

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Authors

Jumpei Hosotani

Mikiko Shibata

Daisuke Yamazaki

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Kidney International Reports

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Tokyo Metropolitan University

Osaka City General Hospital

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WCN26-4437 ASSOCIATION BETWEEN RENAL RESISTIVE INDEX AND DECLINE IN eGFR IN PATIENTS WITH BIOPSY-PROVEN IgA NEPHROPATHY

Key Points

Abstract

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