WCN26-7303 Gross hematuria as a manifestation of LAMA5-Related Nephropathy

Results: Mean age of participant was 56.80 years.Female constituted 60.6%.Hypertension, diabetes mellitus (DM), overweight, obesity and family history of kidney disease were found in 12%, 5.8%, 17%, 30.4% and 2.2% respectively.11.7% of the participants were smokers.Proteinuria was detected in 3.5% and e-GFR # 60 was detected in 18.6%.Both proteinuria and e-GFR # 60 was detected in 1.2%.The participants with DM and hypertension who were receiving treatment were found to be 4.3% and 7.9% respectively.CKD was detected in 0.51% of participants with DM and in 0.84% with hypertension.Out of participants with proteinuria, 0.04% were receiving treatment whereas 0.18% of participants with e-GFR # 60 were receiving treatment.0.01% of participants with both proteinuria and e-GFR # 60 were receiving treatment.All participants who were screened positive were managed as per context specific guidelines.Conclusion: Prevalence of CKD and its risk factors is high in this study, although in the Nepalese context, e-GFR MDRD equation has not been validated yet.Most of the patients with CKD and its risk factors are not receiving the treatment.Community awareness and engagement along with the implementation of the existing guideline can help in early detection and management of CKD and its risk factor in countries with limited resources.I have no potential conflict of interest to disclose.I did not use generative AI and AI-assisted technologies in the writing process.