Thrombotic microangiopathy (TMA) is characterized by endothelial injury leading to microvascular thrombosis, microangiopathic hemolytic anemia, and thrombocytopenia. Distinguishing secondary TMA associated with hypertensive emergencies from atypical hemolytic uremic syndrome (aHUS) is often challenging, as both conditions can present with similar hematologic and renal abnormalities.Moreover, aHUS frequently presents with hypertension, and certain complement gene variants are associated with a slowly progressive clinical course, further complicating the differentiation from hypertension-induced TMA.We report a case of secondary TMA triggered by a hypertensive emergency that closely mimicked aHUS.
Noda et al. (Wed,) studied this question.