Transcatheter aortic valve implantation maintained functional independence comparably to surgical aortic valve replacement at 6 months, with no significant difference in Barthel index scores (p=0.525).
Cohort (n=155)
No
Does TAVI maintain functional status compared to SAVR in elderly patients with symptomatic severe aortic stenosis?
TAVI and SAVR provide comparable 6-month functional stability in older adults with severe aortic stenosis, despite TAVI patients having a higher baseline vulnerability and frailty profile.
Absolute Event Rate: 88.94% vs 90.51%
p-value: p=0.525
Background: Severe aortic stenosis (SAS) is a common valvular disease in older adults, with a prevalence of 9.8% in those aged 80-89 years.Surgical aortic valve replacement (SAVR) is the standard treatment, whereas transcatheter aortic valve implantation (TAVI) has emerged as a less invasive alternative.Functional assessment is crucial for this population.Objective: The objective of the study was to compare functional outcomes in elderly patients with symptomatic SAS undergoing TAVI versus SAVR after 6 months.Material and methods: A retrospective cohort study including patients aged 70 years with SAS treated with TAVI or SAVR between September 2023 and 2024.Functional status was assessed using the Barthel index (BI) at baseline and 6 months.Data were analyzed using descriptive and inferential statistics (Student's t-test) using the Statistical Package for Social the Sciences v25 and Excel.Results: A total of 155 patients were analyzed (TAVI, n = 47; SAVR, n = 108).The TAVI group was older (80 6 vs. 76 4 years, p < 0.05) and had more comorbidities (3 vs. 2) and geriatric syndromes (6 vs. 4) than the surgical group.The baseline BI was similar (89, p = 0.232).After 6 months, functionality remained stable (BI = 90, p = 0.525), with no significant difference in BI change (TAVI -0.53 vs. SAVR + 0.47).Conclusion: Functional status remained stable and comparable between TAVI and SAVR, suggesting similar effectiveness despite higher vulnerability in TAVI patients.
Gómez-García et al. (Wed,) conducted a cohort in Symptomatic severe aortic stenosis (n=155). Transcatheter aortic valve implantation (TAVI) vs. Surgical aortic valve replacement (SAVR) was evaluated on Barthel index score at 6 months (95% CI -6.4-3.3, p=0.525). Transcatheter aortic valve implantation maintained functional independence comparably to surgical aortic valve replacement at 6 months, with no significant difference in Barthel index scores (p=0.525).