What question did this study set out to answer?

To explore the role of cadherin in the differentiation of MSC-derived hepatic organoids at day 14.

April 1, 2026Open Access

Cadherin-mediated differentiation of MSC-derived liver organoids: sequencing at day 14

To explore the role of cadherin in the differentiation of MSC-derived hepatic organoids at day 14.
Conducted single-cell RNA sequencing to assess gene expression profiles.
Focused on cadherin-mediated differentiation in hepatic organoids.
Analyzed multi-lineage development from mesenchymal stem cells.
Identified specific gene expression patterns associated with cadherin-mediated differentiation.
Observed successful formation of multi-lineage hepatic organoids by day 14.
Demonstrated potential for improved understanding of liver development and regeneration.

Single-cell RNA-seq results on day 14 of cadherin-mediated multi-lineage hepatic organoid differentiation from MSCs

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秦政(Jun Yang) (Thu,) studied this question.

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