What question did this study set out to answer?

The aim is to analyze trends in hospitalizations among individuals with HIV in Spain over a 25-year period.

April 3, 2026

Trends in hospitalizations in adults with HIV infection in Spain over 25 years

Key Points

The aim is to analyze trends in hospitalizations among individuals with HIV in Spain over a 25-year period.
Retrospective analysis of the National Registry of Hospital Discharges from 1997 to 2022.
Included all hospitalizations with HIV and/or AIDS diagnoses.
Comparison of hospitalization trends across three distinct periods.
Total hospitalizations decreased by 36.3% over 25 years.
Proportion of admissions with AIDS fell from 76.1% to 64%.
Opportunistic infections declined from 84.7% to 54.8%, whereas AIDS-related cancers rose from 14.1% to 31.5%.
In-hospital mortality decreased from 6% to 4.5%.

Abstract

Given the current high efficacy of antiretroviral therapy and the availability of prophylactic medications, the spectrum of illnesses requiring hospitalization in people with HIV (PWH) has evolved over time. All hospitalizations with a diagnosis of HIV and/or AIDS at the National Registry of Hospital Discharges were retrospectively examined in Spain from 1997 to 2022. There were 610,912 admissions in PWH. Male represented 73%. Mean age at admission was 43.2 years-old and increased from 33.5 years in 1997 to 53.2 in 2022 (p p p p < 0.001). Hospitalizations and mortality among PWH in Spain have decreased over 25 years. While OIs dropped 23.3%, AIDS-related cancers rose by 20%. Mean age at admission reached 53.2 years in 2022.

Trends in hospitalizations in adults with HIV infection in Spain over 25 years

Key Points

Abstract

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