Abstract Background Automated image acquisition in combination with a 2D image navigator allow for an improved spatial resolution of Coronary Magnetic Resonance Angiography (CMRA) that is approaching that of coronary computed tomography angiography. However, it remains unclear whether this increased spatial resolution significantly improves the diagnostic performance of CMRA in detecting the severity of Coronary Artery Disease (CAD). Objectives To compare 0.7 mm³ CMRA to 0.9 mm³ CMRA for the detection of CAD, using 2-dimensional quantitative coronary angiography as the reference standard. Methods 81 patients were recruited to the study. The diagnostic performance of 0.7 mm3 and 0.9 mm3 CMRA to detect ≥50% coronary stenosis was compared on a per-patient and per-vessel basis. Results On a per-patient basis, the sensitivity of 0.7 mm3 CMRA was significantly better than 0.9 mm3 CMRA to detect ≥50% stenosis (0.885 vs 0.721, p = 0.01), whilst the negative predictive value showed no difference (0.500 vs 0.320, p = 0.10). On a per vessel basis, the sensitivity (0.716 vs 0.558, p = 0.01), negative predictive value (NPV) (0.857 vs 0.802, p = 0.01) and Area under the curve (AUC) (0.742 vs 0.682, p = 0.04), were significantly better for 0.7 mm3 CMRA to detect ≥50% stenosis. Conclusions CMRA with an improved spatial resolution of 0.7 mm³ compared to 0.9 mm³ was superior for the detection of ≥50% stenosis.
Wood et al. (Tue,) studied this question.
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