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This article reviews oncoplastic breast surgery to assess its clinical, cosmetic, and oncological outcomes compared to breast-conserving surgery.

April 6, 2026Open Access

Oncoplastic Breast Surgery: Bridging Oncological Safety and Aesthetic Excellence in the Era of Precision Surgery

Key Points

This article reviews oncoplastic breast surgery to assess its clinical, cosmetic, and oncological outcomes compared to breast-conserving surgery.
Review of literature on oncoplastic breast surgery
Comparison of volume displacement and volume replacement techniques
Analysis of oncoplastic surgery classifications
Examination of challenges in OBS adoption worldwide
Oncoplastic breast surgery shows similar survival rates to traditional methods while improving aesthetic outcomes.
Larger tumors can be removed with better cosmetic results using oncoplastic techniques.
Challenges in training and widespread adoption of oncoplastic surgery are highlighted.
Use of artificial intelligence in tissue modeling presents future potential for improved surgical planning.

Abstract

Breast cancer is a significant health problem worldwide, being the most frequent cancer in females and one of the most lethal. The current approach to breast cancer has moved away from the morbid Halsted radical mastectomy to breast-conserving surgery (BCS). Although BCS, supplemented by radiotherapy, has the same survival rates as the Halsted procedure, it is associated with significantly good post-operative outcomes. Oncoplastic breast surgery (OBS) combines the principles of breast cancer removal and reconstruction, allowing for the removal of larger tumors while maintaining the breast appearance by reshaping the breast tissue. In this article, the current evidence for the clinical, cosmetic, and oncological outcomes of OBS is reviewed. The evidence demonstrates the safety and potential benefits of OBS in comparison to BCS in the removal of breast cancer. The article provides a background on the various classifications of OBS, including the evolution from volume-based to ptosis-based classifications by the American Society of Breast Surgeons. A comparison is made between volume displacement techniques, such as therapeutic mammoplasties, and volume replacement techniques, including regional perforator flaps and fat grafts. The article also discusses the challenges facing the adoption of OBS across the world, including the disparity in training between surgeons in developed and developing countries. Additionally, the article presents the challenges facing the adoption of OBS, including the risk of fat necrosis and fibrosis. The article also presents the future direction in the development of OBS, including the use of extreme oncoplastic techniques in the removal of breast cancer using neoadjuvant chemotherapy. Additionally, the article presents the use of artificial intelligence in the pre-operative modeling of breast tissue using robotic-assisted tissue transfer. OBS is the current gold standard in the removal of breast cancer.

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