Perioperative Antidepressant Use Increases the Risk of Opioid Abuse After Total Joint Arthroplasty.

Key Points

• To investigate the relationship between perioperative antidepressant use and the risk of opioid abuse following total joint arthroplasty.
• Conducted a retrospective analysis on opioid use in patients undergoing total joint arthroplasty.
• Assessed antidepressant prescriptions during the perioperative period.
• Evaluated opioid abuse rates post-surgery.
• Patients using antidepressants showed higher rates of opioid abuse compared to those not using them.
• The relationship indicates a significant risk factor for increased opioid dependence.
• Findings suggest careful assessment of antidepressant use before and after surgery.

Abstract