What does this research mean for the field?

A single session of aerobic exercise significantly alters miRNA and transcript levels related to hepatic lipid and muscle glucose metabolism in the male offspring of obese dams, providing acute metabolic benefits against maternal metabolic programming. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

The aim is to evaluate how a single exercise session influences metabolic gene expression in offspring from obese dams.

April 10, 2026

Individualized aerobic session modulates key metabolic genes in liver and muscle of male offspring from obese dams.

Key Points

The aim is to evaluate how a single exercise session influences metabolic gene expression in offspring from obese dams.
Examined the effects of a single exercise session on offspring of obese dams
Analyzed changes in miRNA and transcript levels
Focused on hepatic lipid and muscle glucose metabolism
Significant changes in miRNA levels related to lipid metabolism
Alterations in transcript levels associated with glucose metabolism
Improvements suggest potential long-term benefits of exercise on metabolic health

Abstract

A single session of exercise significantly affected miRNA and transcript levels related to hepatic lipid and muscle glucose metabolism, suggesting that even one bout of exercise can benefit offspring in the context of maternal metabolic programming. This highlights tissue responsiveness and adaptive capacity, warranting further investigation into its potential as a long-term, non-pharmacological intervention.

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Discussion

Authors

Paloma Brasilio Villalta

Laís Angélica de Paula Simino

Thaís de Fante

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Institutions

Universidade Estadual de Campinas (UNICAMP)

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Individualized aerobic session modulates key metabolic genes in liver and muscle of male offspring from obese dams.

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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