What question did this study set out to answer?

To evaluate the expression of E-cadherin in invasive ductal breast cancer and its implications for prognosis.

April 12, 2026Open Access

Evaluation of Е-cadherin expression in invasive ductal breast cancer

ICIlona V. ChelpanovaDanylo Halytsky Lviv National Medical University LVL. I. VolosDanylo Halytsky Lviv National Medical University ADAndrii P. DudashUkrainian Academy of Printing

Key Points

To evaluate the expression of E-cadherin in invasive ductal breast cancer and its implications for prognosis.
Analyzed E-cadherin expression levels in breast cancer tissues
Correlated expression levels with disease outcomes
Investigated the relationship between expression loss and patient prognosis
E-cadherin expression is linked to tumor suppression
Partial or complete loss is associated with poor patient prognosis
Higher loss of E-cadherin correlates with more aggressive disease features

Abstract

Conclusions: E-cadherin is a potent tumor suppressor in breast cancer. Its role in disease progression is confirmed by the correlation between partial or complete loss of E-cadherin expression and poor prognosis for patients.

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