The global rise in interest toward herbal oral care products has brought significant focus on the phytoconstituents present in herbal toothpastes. Unlike conventional formulations containing fluoride, triclosan, and chlorhexidine, herbal preparations utilize natural bioactive compounds such as flavonoids, tannins, terpenoids, alkaloids, and essential oils derived from plants like neem, clove, licorice, and miswak. These phytoconstituents exert antibacterial, anti-inflammatory, antioxidant, and plaque-inhibiting actions that contribute to maintaining gingival health. This review summarizes the mechanisms of plaque formation, the role of active phytoconstituents, their pharmacological actions, and compares them with conventional agents. Safety aspects, current evidence from clinical and laboratory studies, and future research prospects are also discussed to highlight the therapeutic potential of herbal-based oral care products. Keywords: Herbal toothpaste; Phytoconstituents; Dental plaque; Gingival health; Antimicrobial activity
Bhaskar et al. (Wed,) studied this question.