RETRACTION : EP2 Prostanoid Receptor Promotes Squamous Cell Carcinoma Growth through Epidermal Growth Factor Receptor Transactivation and iNOS and ERK1 /2 Pathways

RETRACTION: S. Donnini , F. Finetti , R. Solito , E. Terzuoli , A. Sacchetti , L. Morbidelli , P. Patrignani , M. Ziche , "," The FASEB Journal 21 , no. ( 2007 ): 2418 ‐ 2430 https://doi.org/10.1096/fj.06‐7581com . The above article, published online on 23 March 2007 in Wiley Online Library ( wileyonlinelibrary.com ), has been retracted by agreement between the journal Editor‐in‐Chief, Dr. Loren E. Wold; the Federation of American Societies for Experimental Biology; and Wiley Periodicals, LLC. The journal received allegations by a third party of image reuse and relabeling within the same paper and between others published by a subset of the authors. Further investigation of the article by the publisher confirmed the third‐party concerns and detected evidence of additional image reuse and relabeling. Specifically, images in Figures 1A, 2A, 3B, 4A, 6G, and 7C were reused in part (with or without horizontal flipping) throughout the paper. Multiple figures have inconsistent splicing patterns among panels of the same figure, including, but not limited to: Figure 6G, Figure 7C, and Figure 8D. Figure 1A was reused as Figure 3a and Figure 3b, while Figure 4A was reused as Figure 3a in a article published contemporaneously Donnini et al. 2007 ( https://doi.org/10.1079/bjn20061753 ). Figure 3B was reused as Figure 6D in a later article Finetti et al. 2009 ( https://doi.org/10.1161/circresaha.109.203760 ). The retraction has been agreed to because of the evidence of image duplication in multiple figures and across multiple papers, which fundamentally compromises the editors' confidence in the conclusions presented. The authors disagree with the retraction. Authors P. Patrignani and A. Sacchetti further state that their contributions to the research reported in the article were limited to the western blot shown in Figure 3A.