This paper argues that fascia and the interstitial matrix form a continuous, body-wide transduction substrate that couples mechanical, electrical, hydraulic, chemical, and photonic processes across scales. Drawing on connective tissue biomechanics, interstitial anatomy, integrin-mediated signaling, piezoelectric collagen, structured water, and biophotonic phenomena, we propose that the fascial system is not merely supportive scaffolding but a distributed energy-processing network linking tissue mechanics to cellular regulation and organism-level state. We further suggest that the nervous system evolved into, rather than ex nihilo created, an already-running body-first loop of signaling, integration, and response. This framework generates testable predictions for connective tissue disorders, interoception, movement-based therapies, and open questions in embodied cognition. More speculative extensions explore whether this substrate also helps explain cross-cultural models of qi, altered states, and the phenomenology of felt bodily knowing.
Logan Linthicum (Tue,) studied this question.