From sore throat to sepsis: unmasking life-threatening Lemierre syndrome

Lemierre syndrome is a serious condition that typically affects young, otherwise healthy individuals. It typically begins with a bacterial oropharyngeal infection that progresses to septic thrombophlebitis of the internal jugular vein, frequently accompanied by septic emboli. We present a case involving a previously healthy young male who developed Lemierre syndrome following a sore throat and fever, later complicated by sepsis. Imaging confirmed internal jugular vein thrombosis, and blood cultures grew Fusobacterium necrophorum . Further investigation revealed underlying thrombophilia, which likely contributed to the severity of his thrombotic complications. The patient was successfully treated with broad-spectrum antibiotics and anticoagulation. Although incidence has declined with widespread antibiotic use, this case emphasises the importance of early recognition and prompt treatment to reduce the risk of severe complications and mortality.