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This research aims to evaluate serum levels of acute phase proteins in goats affected by infectious keratoconjunctivitis.

April 23, 2026Open Access

Evaluation of Some Serum Acute Phase Proteins in Goats with Infectious Keratoconjunctivitis in Siirt Province

Key Points

This research aims to evaluate serum levels of acute phase proteins in goats affected by infectious keratoconjunctivitis.
Evaluated 75 goats—50 with infectious keratoconjunctivitis and 25 healthy controls.
Conducted ophthalmic and general physical examinations.
Measured serum levels of specific proteins using ELISA kits.
Significant increases in acute phase protein levels were noted in goats with infectious keratoconjunctivitis.
Bacterial isolation revealed 15 different types of bacteria from eye swabs.

Abstract

The aim of this study was to evaluate certain acute phase proteins in goats with infectious keratoconjunctivitis. For this purpose, a total of 75 goats were used—50 with IKC and 25 healthy controls. After routine general and ophthalmic examinations (body temperature, pulse and respiration rate, lymph node palpation, abdominal palpation, and lung auscultation), eye swabs were collected from goats diagnosed with IKC. A total of 15 different bacteria were isolated from the eye swabs. The serum was separated from the blood samples taken from the goats included in the study and stored at -20 °C until analysis. Serum levels of amyloid A, C-reactive protein, ceruloplasmin, and fibrinogen were measured using commercial ELISA kits. Significant increases in acute phase protein levels were observed in the IKC group. Based on the results, it was suggested that acute phase proteins may be useful indicators for the diagnosis and monitoring of inflammation developing during IKC.

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