Low Anti-Müllerian Hormone (AMH) is a well-established marker of diminished ovarian reserve and is associated with reduced reproductive potential. When coupled with structural uterine abnormalities such as fibroids—particularly large fibroids—the likelihood of natural conception is often considered poor, and assisted reproductive technologies (ART) or surgical interventions are commonly advised. This case report describes Ayurvedic management of a 32-year-old female with secondary infertility, diminished ovarian reserve (AMH: 0.3 ng/mL), and a large intramural uterine fibroid measuring 54×66 mm, resulting in successful conception. The male partner exhibited normospermia, indicating no contributory male factor. A structured and individualized Ayurvedic treatment protocol—including Poshini, Vardhani, Bhedini, and Upaja—was implemented, focusing on enhancing oocyte quality, improving ovarian function, regulating hormonal balance, optimizing uterine health, and addressing fibroid-related pathology. Following three months of consistent treatment along with appropriate lifestyle modifications, spontaneous natural conception was achieved without the use of assisted reproductive techniques or surgical intervention. This case underscores the potential of Ayurvedic management as a non-invasive, holistic approach capable of addressing both functional (ovarian reserve) and structural (fibroid) factors in infertility. It highlights the importance of improving the internal reproductive environment and suggests a promising complementary role for Ayurveda in the management of complex infertility cases.
Dr. Aarati Patil, Dr. Dharati Rajvir, Dr. Kshitija Berde, Dr. Aishwarya Deshpande* (Fri,) studied this question.