Development of an aptamer PEGylation platform for the treatment of infections caused by multidrug-resistant bacteria (MDR)

Key Points

• To develop a new platform using aptamer PEGylation for treating infections from multidrug-resistant bacteria.
• Development of a PEGylation platform using aptamers.
• Evaluation of treatment efficacy against multidrug-resistant bacterial strains.
• Demonstrated effective bacterial growth inhibition in treated samples.
• Achieved significant reduction in infection severity compared to control cases.