Antioxidant and anti-inflammatory effects of Boswellia andChrysanthemum zawadskii extract mixture on PM2.5-stimulated RAW264.7 cells

Key Points

• This research aims to evaluate the combined antioxidant and anti-inflammatory effects of Boswellia and Chrysanthemum zawadskii extracts on PM2.5-stimulated RAW264.7 cells.
• Developed a mixed extract from Boswellia and Chrysanthemum (FRH-CB) for evaluation.
• Assessed the effects of FRH-CB on PM2.5-stimulated RAW264.7 cells.
• Evaluated changes in MAPK, NF-κB, and PI3K/Akt pathways in response to treatment.
• FRH-CB significantly inhibited the expression of iNOS and COX-2 in PM2.5-stimulated cells.
• Treatment restored HO-1 expression that was decreased by PM2.5 exposure.
• Results indicate the potential of FRH-CB to mitigate inflammatory damage caused by air pollution.

Abstract