Abstract Background This study aims to validate the suitability of the Inventory of Depressive Symptomatology Self-Report (IDS-SR) for evaluating mood disorders in older adults with subjective cognitive decline (SCD) and mild cognitive impairment (MCI). Methods A total of 1670 participants aged ≥ 50 years were included (531 males; mean age 65.79 ± 7.39 years). Construct validity of the IDS-SR was evaluated using exploratory factor analysis (EFA) and confirmatory factor analysis (CFA). Criterion validity was examined using Pearson correlation analyses between IDS-SR scores and scores on the Hamilton Depression Scale (HAMD) and the Hamilton Anxiety Scale (HAMA). Receiver operating characteristic (ROC) curve analysis was conducted to determine the ability of the IDS-SR and its subscales to distinguish mood disorders in SCD and MCI. Cronbach’s α and the intraclass correlation coefficient (ICC) were employed to assess the reliability of the scale. Results The EFA demonstrated that the major factors explained 47.722% of the total variance. The CFA confirmed a three-factor model of the IDS-SR and indicated good construct validity. The fit indices were as follows: chi-square/degree of freedom ( χ 2 / df ) = 3.316, root mean square error of approximation (RMSEA) = 0.054, goodness of fit index (GFI) = 0.945, adjusted goodness-of-fit index (AGFI) = 0.928, comparative fit index (CFI) = 0.921, incremental fit index (IFI) = 0.922, and Tucker-Lewis index (TLI) = 0.908. The total Cronbach’s α was 0.839. The ICC for the total scale was 0.952. Conclusions The IDS-SR scale is a reliable and valid screening tool for detecting mood disorders in older adults with SCD and MCI. This study provides the first validation of the scale in this population.
Wang et al. (Mon,) studied this question.