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The report aims to summarize key insights and advances in biotransformation discussed at the workshop.

May 14, 2026

Meeting report of the 6th European Biotransformation Workshop

MAM. AhlqvistAstraZeneca (Finland)MWM. WallesPharmacoGenetics (China)EIE.M. IsinUniversité Paris-Saclay

Key Points

The report aims to summarize key insights and advances in biotransformation discussed at the workshop.
Presented advancements in biotransformation applications using Accelerator Mass Spectrometry (AMS).
Reviewed new approach methodologies and guidance for assessing metabolites in humans.
Highlighted new in vitro systems to study metabolism and toxicity.
Introduced innovative tools for metabolite assessment in human studies.
Showcased advancements in assessing metabolism and potential toxicity through new in vitro systems.

Abstract

Challenges, strategies and new technologies in the field of biotransformation were presented and discussed at the sixth European Biotransformation Workshop which was held on September 1, 2025, at Churchill College in Cambridge, UK. This meeting report summarises the workshop presentations and discussions.The topics covered are listed below:Recent advances in development biotransformation applications with Accelerator Mass Spectrometry (AMS)New approach methodology (NAM) and guidance's to assess metabolites in humansNew in vitro systems to assess metabolism and toxicity.

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