A Proper Definition of Neuromodulation as Superposition of Two Electric Currents

Abstract- While neuromodulation represents a successful technique for therapy of critical mental and health cases, there is not a universally accepted mechanism of how its applying may change the electrical activity of neurons and influence the flow of nerve impulses through axons. As an approach to find plausible explanation of the measured impacts of such technique, we followed an innovative definition of the nerve impulses as electric charges since the electric charges were recently defined as electromagnetic waves that have electric potential. Such approach succeeded in finding plausible explanation of how the flow of nerve impulses from neurons through the neural fibers was measured as electric signals associated by recorded moving potentials which was traditionally called “action potential.” Such approach also led to define the neurons as thermo-cells that convert their metabolic heat into electric nerve impulses and the axons as transmission lines of such impulses. In the present study, we extend the application of this approach to recognize the neuromodulation as superposition of the modulating electric current and the current of flowing nerve impulses through axons. Such conclusion succeeds to plausibly explain the recorded impacts of neuromodulation on activation or deactivation of generation of nerve impulses and on strengthening or retarding the flows of nerve impulses through the axons according to the polarity of the modulating current. Understanding the current density as a property that depends on the entropy growth rate through the neural conductors, it was possible to determine the value of a proper threshold power of the injected or induced current that may excite the neural systems.