Jaw lesions present a broad spectrum of origins and behaviors, making accurate recognition, diagnosis, and appropriate management essential. This report describes a 35-year-old woman presenting with pain in the lower right posterior mandible, lingual swelling, extrusion of tooth 46, and grade III mobility of tooth 47. Radiographic evaluation revealed a well-defined multilocular radiolucent lesion extending into the mandibular ramus, with cortical perforation and inferior displacement of the mandibular canal. Histopathological analysis confirmed a low-grade intraosseous mucoepidermoid carcinoma (IMEC). The patient underwent segmental mandibulectomy with fibula free flap reconstruction, cervical dissection, and adjuvant radiotherapy and chemotherapy due to soft tissue invasion and compromised margins. She remains disease-free at the two-year follow-up. Despite its rarity, IMEC should be considered in the differential diagnosis of multilocular radiolucent mandibular lesions. Early diagnosis, radical surgical management, and interdisciplinary follow-up are essential for optimal outcomes.
Santos et al. (Fri,) studied this question.
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