A systems-level conceptual perspective proposing that stable biological change in complex adaptive systems may emerge not primarily through targeted intervention, but through the reduction of interference within coherent systemic conditions.The article examines the limitations of intervention-based biomedical models and introduces non-interference as an alternative framework for understanding biological reorganization, microbiome dynamics, and systemic coherence.The perspective is grounded in longitudinal observational evidence interpreted through systems biology and ecological theory, and discusses the role of structured fermented nutritional systems (SAFS — Stabilized Active Fermentation Structures) within a non-intervention paradigm.
Pascu et al. (Sat,) studied this question.
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