In this issue, Wang et al. (https://doi.org/10.1083/jcb.202509044) report that in the syncytial fungus Neurospora crassa, the core proteins regulating circadian rhythms are shared between adjacent nuclei. They also show that core circadian proteins form highly dynamic nuclear bodies that oscillate in both abundance and colocalization, indicating potential for switch-like spatiotemporal regulation of circadian transcription.
Coveney et al. (Fri,) studied this question.