Introduction: Anaphylaxis is defined by the World Allergy Organization as a rapidly developing, potentially fatal systemic hypersensitivity reaction. Clinical manifestations may include cutaneous, respiratory, and cardiovascular involvement, with edema of the tongue and oropharyngeal region representing the most life-threatening presentation.Case Report: Two anaphylactic reactions occurring after local anesthetic administration are presented. A 37-year-old male patient undergoing mandibular molar extraction and a 42-year-old female patient scheduled for implant surgery developed dyspnea, dysphagia, and acute soft-tissue edema of the pharyngeal region. Following early diagnosis and emergency intervention, both patients were stabilized and referred for further management. Subsequent allergological evaluation confirmed articaine hypersensitivity in both cases, and the planned procedures were successfully completed using mepivacaine hydrochloride as an alternative local anesthetic agent.Conclusion: Increasing clinicians' awareness and knowledge regarding the risk of anaphylaxis in dental practice is of critical importance for patient safety.
Dağal et al. (Wed,) studied this question.