柴枳导滞方联合推拿手法在小儿便秘中的应用及对血清炎症因子的影响研究

Key Points

• This study aims to explore the effects of Chai-Zhi Da-Zhi formula combined with massage techniques on pediatric constipation and serum inflammatory factors.
• 112 pediatric constipation patients from Shouguang Traditional Chinese Medicine Hospital were selected from March 2022 to February 2024.
• Participants were divided into control and observation groups, each with 56 cases, receiving different treatment regimens for 2 weeks.
• Assessment included TCM syndrome scores, gastrointestinal hormone levels, inflammatory factors, and safety.
• The observation group showed a significantly lower TCM syndrome score than the control group after treatment (P<0.05).
• Both groups had increased levels of motilin, gastrin, and ghrelin after treatment, with the observation group showing higher levels (P<0.05).
• Interleukin-6, interleukin-8, and tumor necrosis factor-alpha levels decreased post-treatment in both groups, with the observation group lower than control (P<0.05).

Abstract