What question did this study set out to answer?

This research aims to evaluate the effectiveness of an HIV/STD risk-reduction intervention in decreasing forced sex perpetration and experience among adolescents.

May 25, 2026Open Access

Effect of a behavioral intervention on perpetrating and experiencing forced sex among South African adolescents: a secondary analysis of a cluster-randomized trial

Key Points

This research aims to evaluate the effectiveness of an HIV/STD risk-reduction intervention in decreasing forced sex perpetration and experience among adolescents.
Cluster randomized trial conducted in schools in Eastern Cape Province, South Africa.
1057 students enrolled from matched pairs of schools, focusing on those not reporting forced sex before intervention.
Generalized estimating equation Poisson regression analyses were used for data analysis adjusting for gender and school clustering.
Significant reduction in the perpetration of forced sex was observed post-intervention with a pronounced effect noted at 12 months (OR, 0.45; 95% CI, 0.30-0.67; p<0.001).
Experience of forced sex also significantly decreased among participants over the follow-up period, especially noted at 54 months (OR, 0.56; 95% CI, 0.38-0.82; p=0.004).
The intervention showed lasting effects in reducing sexual risk behaviors in the target population.

Abstract

Scant research has investigated interventions to reduce forced sexual intercourse among adolescents. The need for such interventions is especially great in South Africa, which has some of the highest rates of sexual assault in the world. The objectives were to determine whether an HIV/sexually transmitted disease risk-reduction intervention that reduced sexual risk behavior and sexually transmitted disease prevalence also reduced the perpetration and experience of forced sex among South African adolescents. A cluster randomized clinical trial, at schools located in a township and a semi-rural area, Eastern Cape Province, South Africa. Matched pairs of schools were randomly selected (9 of 17); of 1118 students in sixth grade at these 18 schools who had parent or guardian consent, 1057 (94%) were enrolled, and those not reporting forced sex perpetration before the intervention were included in the analyses (n = 1052). Post hoc secondary analysis of a cluster randomized clinical trial was performed, with baseline and 3-, 6-, 12-, 42-, and 54-month post intervention assessments between October 4, 2004, and June 30, 2010. Generalized estimating equation Poisson regression analyses adjusting for gender and clustering within schools were conducted between August 23, 2017, and April 30, 2018. Recruiters and data collectors, but not intervention facilitators, were blind to the participants' intervention assignment. Theory-based, culturally adapted, 6-session HIV/sexually transmitted disease risk-reduction intervention (Let Us Protect Our Future intervention) and attention-matched, chronic disease prevention control intervention implemented by specially trained man and woman co-facilitators from the community. Study outcomes for this secondary analysis (planned after the data were collected) are self-reports of perpetrating and experiencing forced vaginal intercourse.

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