Vesicular Assemblies of Non-ionic Surfactants Niosomes: Design, Preparation, and Applications in Drug Delivery

As long-lasting, biodegradable, low-toxicity, and economically appealing vesicular nanocarriers, niosomes offer an intriguing replacement for lipid-based systems, for example, lipo-somes. As a means to get past major challenges in drug delivery, including drug instability, rapid degradation, lower bioavailability, and insolubility, this review underscores their critical relevance as reconfigurable nanocarriers. Ever since L'Oréal's landmark approval in 1975 for use in beauty prod-ucts, niosomes have shown remarkable potential for precisely delivering a vast array of therapeutic compounds. This comprises chemicals that are antimicrobial, antibacterial, anti-inflammatory, anti-oxidant, as well as in chemotherapy. Considering niosomes' common application in cosmetics, their demonstrated effectiveness in research also extends to a number of various other uses. These include supporting gene therapy, supporting the treatment of cancer, combating infections, and operating as adjuvants for medication. These results underscore the flexible nature of niosomes as biocompatible nanocarriers that provide a range of therapeutic compounds with increased stability, much greater bioavailability, and controlled release. Niosomes have unquestionably been positioned as a major de-velopment in drug delivery technology based on this centre of investigations.