Cardiac magnetic resonance imaging successfully differentiated recurrent cardiac myxomas from thrombi in a 14-year-old female with Carney complex, guiding a second successful surgical resection.
Case Report (n=1)
Cardiac magnetic resonance imaging plays a critical role in differentiating thrombus from recurrent tumor in patients with Carney complex, thereby optimizing therapeutic decision-making and avoiding unnecessary interventions.
Background Carney complex is a rare autosomal dominant syndrome characterized by multiple cardiac myxomas with early onset and high recurrence rates, associated with a significant risk of intracardiac obstruction and embolic events. Case Presentation A female patient was diagnosed at age 14 with multiple intracardiac masses involving both atria and the right ventricle, which were confirmed as myxomas and surgically resected. She also presented with mucocutaneous lentiginosis and a pituitary microadenoma, establishing a clinical diagnosis of Carney complex despite negative genetic testing. During follow‐up, new masses were initially interpreted as intracardiac thrombi and treated with anticoagulation but were subsequently reclassified as tumor recurrence based on multimodal imaging. Progressive tumor burden led to a second surgical intervention with complete resection of multicameral lesions, with favorable clinical evolution. Conclusion This case illustrates the systemic and recurrent nature of Carney complex and highlights the critical role of cardiac magnetic resonance imaging in differentiating thrombus from tumor, optimizing therapeutic decision‐making, and avoiding unnecessary interventions.
Abarca-Rozas et al. (Thu,) conducted a case report in Carney complex with multiple cardiac myxomas (n=1). Surgical resection and cardiac magnetic resonance imaging was evaluated. Cardiac magnetic resonance imaging successfully differentiated recurrent cardiac myxomas from thrombi in a 14-year-old female with Carney complex, guiding a second successful surgical resection.