What question did this study set out to answer?

This research aims to evaluate the reporting of results among oncology trials in African countries and identify factors associated with better reporting.

May 29, 2026

Trial characteristics and results reporting among oncology clinical trials involving African countries.

Key Points

This research aims to evaluate the reporting of results among oncology trials in African countries and identify factors associated with better reporting.
Identified 1,140 completed oncology trials from ClinicalTrials.gov involving ≥1 African site (1992-2023).
Classified trials by country, institution, region, and funder, analyzing proportions and using multivariable logistic regression.
Measured results reporting rates and identified determinants associated with disclosure.
Overall, 25.2% of trials posted results, with multi-country trials reporting more (59.7%) than single-country (22.8%).
Industry-sponsored trials (70.5%) reported results significantly more than non-industry trials (4.6%).
Phase III trials showed higher reporting rates (64.0%) compared to other trial phases (10.6%).

Abstract

1589 Background: Sub-Saharan Africa (SSA) faced ~801,000 new cancer cases and ~520,000 cancer deaths in 2020, with deaths projected to reach 1 million annually by 2030. African trial activity remains scarce (100 (ref: ≤100) 1.89 (1.32-2.71) 0.001

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