What is the clinical evidence from this study?

Study design: Case Report. Population: Dengue myocarditis (n=1). Intervention: Cautious fluid management and supportive care. Primary outcome: Ejection fraction.

What question did this study set out to answer?

This case discusses the occurrence of severe systolic dysfunction due to myocarditis in a patient with dengue fever.

May 30, 2026Open Access

Severe Acute Global Systolic Dysfunction Secondary to Dengue Myocarditis: A Case Report

Q: What does this research mean for the field?

Severe acute global systolic dysfunction secondary to dengue myocarditis is a reversible complication that requires early detection and judicious fluid management to avert cardiac decompensation. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Key Result

Cautious fluid management and supportive care in a 47-year-old woman with severe dengue myocarditis improved left ventricular ejection fraction from 20% to 40%.

Key Points

This case discusses the occurrence of severe systolic dysfunction due to myocarditis in a patient with dengue fever.
Described the clinical presentation and echocardiographic findings of a 47-year-old woman.
Monitored cardiac function during intensive care with controlled fluid therapy.
Followed up with echocardiography at three months to assess recovery.
Initial ejection fraction was 20%, indicating severe left ventricular dysfunction.
At three-month follow-up, ejection fraction improved to 40% with symptom resolution.
Emphasized the need for early detection and careful management in dengue cases with cardiac symptoms.

Study Design

Type

Case Report (n=1)

Structured PICO

Population

47-year-old woman with laboratory-confirmed dengue fever who developed acute myocarditis and severe left ventricular systolic dysfunction (LVEF 20%) during the critical phase of illness (n=1).

Intervention

Cautious fluid management and inotropes in the intensive care unit.

Outcome

Improvement in ejection fraction and resolution of symptoms at three-month follow-up.surrogate

Highlights the importance of early detection and judicious fluid management in dengue myocarditis to avert cardiac decompensation and improve prognosis.

Limitations

In the absence of cardiac MRI or endomyocardial biopsy, a definitive histopathological diagnosis of dengue myocarditis could not be established.
Long-term follow-up beyond the early recovery period was limited.

Abstract

We describe the case of a 47-year-old woman with laboratory-confirmed dengue fever who developed acute myocarditis during the critical phase of illness. On presentation, along with her initial symptoms of fever, headache, and myalgia, she also reported central chest discomfort and exertional dyspnoea. A standard transthoracic echocardiogram demonstrated severe left ventricular systolic dysfunction with an ejection fraction of 20%. She was treated in the intensive care unit with cautious fluid because of the risk of volume overload in dengue with cardiac involvement. She was able to come off inotropes after the acute phase of illness, and echocardiography at the three-month follow-up revealed improved ejection fraction to 40% and resolution of symptoms. This case points out the need for early detection of myocardial involvement in dengue infection and the importance of judicious fluid management to avert cardiac decompensation and improve prognosis.

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