Hair loss and thinning are widespread cosmetic and clinical concerns affecting individuals across all demographics, commonly associated with androgenetic alopecia, oxidative follicular damage, and DHT-mediated follicle miniaturisation. Herbal formulations are attracting considerable scientific attention as safer, patient-acceptable alternatives to synthetic pharmacological agents. The present study describes the development and physicochemical characterisation of a polyherbal hair growth serum incorporating ethanolic rosemary (Rosmarinus officinalis L.) extract as the primary bioactive constituent, augmented with aqueous fenugreek (Trigonella foenum-graecum L.) seed extract, aloe vera gel, glycerine, vitamin E, and parabens as preservatives. Rosemary and fenugreek extracts were individually prepared by cold maceration and evaluated for their synergistic potential in addressing androgenic alopecia through 5-alpha reductase inhibition, antioxidant protection, keratin precursor supply, and follicular vasodilation. The serum was formulated at a fixed 50 mL batch and subjected to comprehensive physicochemical evaluation encompassing appearance, pH, viscosity, spreadability, and homogeneity. All parameters met the predefined acceptance criteria: the formulation presented as a clear, slightly hazy pale amber liquid with a characteristic herbal aroma; pH of 5.09 (range 5.0–6.5); viscosity of 2198 cP (target 1500–2500 cP); uniform spreadability, and satisfactory homogeneity without phase separation or visible particulates. These findings substantiate the feasibility of the rosemary–fenugreek polyherbal serum as a stable, scalp-compatible cosmeceutical candidate for the management of hair loss and scalp health promotion.
Monika Devi*, Nariender Singh1, Mahima2, Shookur Ahmed3, Vansh4, Dr. Kapil Kumar Verma5 (Mon,) studied this question.