Recent advances in biology have led to a transformation of the biotechnology toolbox and the use of the cell as a biomaterial factory, which opens a new area of design approaches for architecture in response to biomaterial problems.The purpose of this research is to develop a framework for computational design and biofabrication in living cell architecture using documentary methods, deductive, logical, and experimental reasoning, with the help of cell science metaphors, and Turing morphogenesis.The structure of the proposed framework based on the Rubik's model consists of four parts: information unit, computation logic, interaction field, and multipurpose tool, in which the "cell" is presented as a renewable and programmable tool and building block.We present a reusable design lens, three programmable pathways (gene, epigene, and morphogen), and an in vitro-studio operational model with Acetobacter xylinum dependent on oxygen parameters over a 7 and 14 day time period, and investigate it with material detection experiments.The results show that this bacterial cell, as a multiaxial biomicroprinter, has the ability to produce bacterial cellulose with a porous structure, 20 to 50 nm fibers, a tensile strength of 36 MPa in 14 days, a water absorption capacity of 98%, hydrophilic behavior with a contact angle of 41 degrees, and 23-day biodegradation, which suggests it as an absorbent and environmentally friendly material for use in temporary and responsive skins with an ecological approach.
Yazdani et al. (Sat,) studied this question.