What question did this study set out to answer?

This research aims to compare the effectiveness and safety of dual antiplatelet therapy and intravenous thrombolysis in minor ischemic stroke patients.

June 7, 2026Open Access

Comparison of DAPT and Thrombolysis in Minor Stroke with Regard to Efficacy: A Meta-Analysis

Key Points

This research aims to compare the effectiveness and safety of dual antiplatelet therapy and intravenous thrombolysis in minor ischemic stroke patients.
Conducted a meta-analysis of existing studies on DAPT and IVT in minor ischemic stroke
Evaluated outcomes such as functional recovery, risk of symptomatic intracranial hemorrhage, and mortality
DAPT showed a favorable profile for functional recovery compared to thrombolysis
IVT was associated with a higher risk of symptomatic intracranial hemorrhage
Mortality rates were comparable between the two treatment options

Abstract

Objective Minor ischemic stroke (NIHSS ≤ 5) presents a therapeutic dilemma, balancing the potential benefits of intravenous thrombolysis (IVT) against its hemorrhagic risks, with dual antiplatelet therapy (DAPT) established for recurrence prevention. This meta-analysis compares the efficacy and safety of dual antiplatelet therapy (DAPT) versus intravenous thrombolysis (IVT) in patients with minor stroke, examining functional recovery, the risk of symptomatic intracranial haemorrhage (SICH) and mortality.

Ask AI

Helpful

Bookmark

View Full Paper