A 12-week movement breaks intervention did not improve triple ABC target achievement (P=0.18) but reduced systolic blood pressure by 5.4 mmHg (95% CI -8.3 to -2.5; P<0.001).
RCT (n=69)
randomized
Do brief, intermittent movement breaks (high or low intensity) improve cardiovascular risk factors (ABC targets) in adults living with type 2 diabetes?
Brief, intermittent movement breaks of either high or low intensity over 12 weeks significantly improved blood pressure and A1c target achievement in adults with type 2 diabetes.
p-value: p=0.18
Introduction and Objective: Exercise can improve cardiovascular risk factors including the ABC target (i.e. hemoglobin A1c7.0%; Blood pressure130/80 mmHg; LDL-Cholesterol2 mmol/L) in people living with type 2 diabetes (T2D). However, the impact of brief, intermittent movement breaks on these parameters remains unknown. The objective of the present study was to assess the impact of a 12-week movement breaks intervention on the ABC target and its components. Methods: Adults living with T2D (46 females; 23 males) were randomized to movement breaks performed at either a high-intensity (i.e., “exercise snacks”; n=31) or low-intensity (n=38) under free-living conditions. Participants were instructed to complete 4 × 1-min movement breaks per day on at least 5 d per week (target ≥20 per week). The intervention was delivered through a smartphone application that provided customizable prompts and demonstration videos. ABC target components were measured before and after the 12-week intervention. Results: The proportion of individuals achieving targets increased from 72% to 79% (P=0.02) for A1c, and from 54% to 61% for blood pressure (P=0.04), while those reaching the LDL-C target was unchanged (49 to 53%; P=0.37; all main effects of time). The proportion of participants achieving the triple ABC target did not change from baseline to post-intervention (21 to 27%; P=0.18). Between-group differences at 12 weeks were also not different (P≥0.13). When treated as continuous variables, a main effect of time was observed for systolic (-5.4 -8.3 to -2.5 mmHg, P0.001) and diastolic (-3.5 -5.2 to -1.8 mmHg, P0.001) blood pressure, with no difference between groups (P≥0.15). There were no main effects of time or between-group differences for A1c and LDL-Cholesterol (all P≥ 0.18). Conclusion: A 12-week movement breaks intervention - performed at either high- or low-intensity - improved cardiovascular risk markers, including lowering blood pressure and increasing the proportion of individuals achieving A1c and blood pressure targets. Disclosure A. Marcotte-Chénard: None. R.E. Sandilands: None. F.J. Babir: None. S.F. McCarthy: None. N. Mulkewich: None. A. D'Amico: None. K. Falkenhain: None. H. Islam: None. M. Gibala: Stock/Shareholder; Current; Longevity League Ltd. Advisory Panel; Current; Longevity League Ltd. J. Little: None. Funding Diabetes Canada
MARCOTTE-CHÉNARD et al. (Fri,) conducted a rct in Type 2 diabetes (n=69). High-intensity movement breaks vs. Low-intensity movement breaks was evaluated on Triple ABC target (hemoglobin A1c<7.0%; Blood pressure<130/80 mmHg; LDL-Cholesterol<2 mmol/L) (p=0.18). A 12-week movement breaks intervention did not improve triple ABC target achievement (P=0.18) but reduced systolic blood pressure by 5.4 mmHg (95% CI -8.3 to -2.5; P<0.001).