Introduction and Objective: The prevalence of diabetes continues to rise, and recent estimates indicate that 38% of US adults have prediabetes. With this trend, patient-centered and proactive strategies are essential. As continuous glucose monitors (CGMs) are now accessible over-the-counter, there is ongoing interest in their use beyond patients with established diabetes. Patient-facing data can offer real-time feedback which may inform lifestyle modification. We aimed to evaluate the acceptability of CGM use among participants with prediabetes as a first step toward more proactive care. Methods: Adult participants with prediabetes from a primary care clinic in Boston, MA were identified based on HbA1c (5.7-6.4%) and ICD-10 codes. Participants were mailed a Dexcom Stelo CGM and attended a remote onboarding session with the study team for assistance with sensor placement and set up. Our primary outcome was acceptability as measured by the CGM Satisfaction Scale (CGM-SAT) following the CGM wear period (15 days). Exploratory outcomes included time in tight range (TITR) and coefficient of variation (CV). All analyses were completed in R (version 4.5.2). Results: The cohort included 13 participants who were primarily White (N=7, 53.8%) and female (N=8, 61.5%) with a mean age of 62.7 years (standard deviation (SD): 9.81) and a mean hemoglobin A1c of 6.0% (SD: 0.24). The mean CGM-SAT score was 4.20 (SD: 0.87), indicating high satisfaction. Twelve (92.3%) participants strongly agreed or agreed that they would want to use a CGM when the research study was over. The participants had a mean TITR of 84.7% (SD: 12.10) and mean CV of 16.5% (SD: 3.87). Conclusion: We found high satisfaction with CGM use among participants with prediabetes, indicating potential use for prediabetes care. Study limitations include the single-site design, a small sample size, and only English-speaking participants. Access to CGM may empower patients with prediabetes, fostering engagement and supporting proactive, personalized diabetes prevention. Disclosure N.A. Prada-Rey: None. N. Palermo: Research Support; Ended; Dexcom, Inc. J.A. Rodriguez: None. Funding Brigham and Women's Research Institute
PRADA-REY et al. (Fri,) studied this question.