2331-P: Prevalence of Diabetes in Youth Aged 0–17 Years in a Large, Integrated Health Care Delivery System in California, 2018 and 2024

Introduction and Objective: Diabetes in youth is associated with acute complications and has significant implications for long-term health. We estimated the prevalence of diabetes in youth 0-17 years in Kaiser Permanente Southern California in 2018 and 2024. Methods: Denominators were based on membership counts of youth 18 years of age on December 31 each year with at least 6 months of continuous membership (except those 1 year of age). Prevalence (cases/1000 youth) of type 1 diabetes (T1D) and type 2 diabetes (T2D) were determined by ICD-10 diagnosis codes for each year using a look-back to January 1, 2016. Diabetes type was defined as the type-specific majority of codes occurring over 1 year. Prevalence was calculated overall and by type and demographics. Results: Prevalence of T1D increased from 1.63 to 1.73/1,000 between 2018 and 2024, with increases among all age, sex, and race/ethnicity groups except for Black youth. (Figure) Prevalence of T2D increased from 0.52 to 0.91/1,000 between 2018 and 2024, with increases in all demographic groups. The largest increases for both diabetes types occurred in youth 5-9 years of age. Conclusion: Increasing prevalence in youth is consistent with prior diabetes surveillance network findings in the US. The substantial rise in children 5-9 years highlights the importance of early detection, timely diagnosis and strategies to mitigate complication and support management from an early age. Disclosure M. Mefford: Research Support; Current; Merck Ended; Merck & Co., Inc.