Colorectal cancer (CRC) is a significant cause of mortality globally, with a rising incidence in the Middle East. Understanding CRC screening awareness among the Syrian population is crucial for effective public health interventions. We conducted a cross-sectional study from September 22 to October 15, 2023, with 928 participants. Data were collected via an online questionnaire covering sociodemographic, knowledge, and attitude sections. Descriptive statistics, chi-square tests, and regression were used for analysis with Statistical Package for Social Sciences v28.0. The study revealed a concerning lack of awareness regarding CRC screening among Syrians, with only 52.6% of participants familiar with early cancer screening tests and 48.4% showing adequate knowledge. Knowledge was significantly associated with gender, family history, employment, education, and economic status ( P < .05). The logistic regression model was highly significant ( P < .001, χ 2 = 73.19). Binary regression showed higher odds of insufficient knowledge among participants aged 36 to 40 ( P = .049) and those with poor economic status ( P = .001). Middle school education was protective ( P = .022). Gender and employment showed trends but were not significant. The findings underscore the necessity for public health initiatives to enhance CRC screening knowledge in Syria. Tailored educational programs and increased access to screening facilities are essential for improving early detection and reducing the burden of CRC. Efforts to boost public understanding and engagement in CRC screening are critical for lowering incidence and mortality rates.
Alabed et al. (Fri,) studied this question.