Integrated care is increasingly shaped by digital infrastructures, data governance, and AI-enabled analytics, yet the relevant literature remains fragmented across health-services research, digital health, and machine learning. This article reports a scoping review, conducted in line with PRISMA-ScR guidance, that maps how integrated care models have evolved conceptually, what digital and AI-enabled infrastructures support them, how their clinical, economic, and equity impacts can be evaluated, and what current implementations imply for sustainable scaling. We searched PubMed, Scopus, Semantic Scholar, and Crossref (retrieval date 31 October 2025; forward screening to 31 March 2026) and added grey literature from named policy bodies. The searches identified 15,189 records, reducing to 11,789 after intra- and cross-source deduplication and grey-literature integration; 620 full texts were assessed and 192 were included in the synthesis. Four domains were synthesised: conceptual foundations of integrated care, AI and multimodal analytics, implementation barriers, and digital-governance foundations. We chart the field using a Type I–V maturity scheme (disease, cohort, whole-system, digital-integrated, learning), benchmarked against the Rainbow, MacColl, EMRAM/AMAM, and NHS ICS models. Most deployments cluster at digitally integrated but only weakly adaptive Type IV; recurrent failure modes—temporal blind spots, maintenance debt, semantic drift, and governance gaps—block progression to Type V, and high-profile clinical-AI failures illustrate the cost of attempting Type V analytics on Type IV-or-worse infrastructure. A walk through nine world regions maps each to its current Type I–V position and shows that organisational and payment integration—not digital sophistication alone—is currently the dominant driver of progress. The COMFORTage Integrated Care Model Library is positioned as a workflow of AI agents orchestrating predictive, preventive, and personalised care across the integrated-care lifecycle rather than as a single federated-learning programme. The review positions AI-enabled integrated care less as a finished model than as an emerging design space requiring longitudinal data assets, stewarded model lifecycles, accountable governance, and outcome-based contracting for clinically useful, equitable, and trustworthy learning systems.
Tsitiridis et al. (Mon,) studied this question.