Frontiers in Raman Nano-diagnostics: SERS and TERS of Extracellular vesicles for Cancer Detection

Key Points

• The research aims to explore the use of extracellular vesicles in cancer diagnostics through advanced Raman techniques.
• Utilized surface-enhanced Raman scattering (SERS) and tip-enhanced Raman scattering (TERS) for analysis.
• Focused on isolation and characterization of extracellular vesicles from biological samples.
• Employed specific biomarker detection strategies for cancer identification.
• SERS and TERS effectively detected molecular signatures in extracellular vesicles.
• Achieved high sensitivity and specificity in distinguishing cancerous from non-cancerous samples.
• Provided a promising non-invasive approach for early-stage cancer diagnosis.