Abstract: This review examined advancements in the design of drug delivery systems, which have been significantly driven by an improved understanding of drug pharmacokinetics and pharmacodynamics. These developments, termed novel drug delivery systems (NDDS), provide a more systematic approach to enhancing therapeutic effectiveness. The success of drug delivery research in recent years has largely relied on interdisciplinary collaboration. Pharmaceutical companies have benefited from substantial market opportunities and expanded treatment options, as NDDS improve the safety and efficacy of both synthetic medicinal products and herbal prod-ucts while optimizing their delivery mechanisms. Herbal medicines, long recognized for their therapeutic potential, have faced challenges in standardization, extraction, processing, and solu-bility, which historically limited their development. However, technological advancements have enabled the application of NDDS to create effective herbal drug delivery systems for disease treatment. These systems enhance the stability, bioavailability, and protection of herbal formula-tions as well as synthetic active pharmaceutical agents, preventing degradation and reducing tox-icity risks. This review focuses on the transformative potential of NDDS in improving patient care and reshaping therapeutic practices by analyzing their preparation methods, diverse applica-tions, benefits and limitations, recent patents, marketed preparations of various novel drug deliv-ery formulations, and future perspectives.
Dhage et al. (Tue,) studied this question.
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