Abstract Hemorrhoids are a common anorectal condition among adults worldwide. A large number of patients in India consult homeopathic practitioners for this condition. Our objective is to present the study protocol of a systematic review to evaluate the existing evidence concerning the effectiveness and clinical outcomes of homeopathic treatment for hemorrhoids in an Indian population. Literature databases to search will include MEDLINE, EMBASE, CENTRAL, AMED, CAM-Quest, CORE-Hom, Chiro ACCESS, and LILACS for the period January 2000 to October 2025. The review will include trials with individualized homeopathic medicines, specific medicines, and anti-miasmatic, constitutional or organopathic approaches. The primary outcomes of the review are changes in individual or overall symptom score of hemorrhoids recorded on any validated general or disease-specific scale or quality-of-life score. The secondary outcomes are a change in any symptom recorded by a physician, adverse events, and the prescription of conventional medication. The Cochrane risk-of-bias tool for randomized controlled trials and the Joanna Briggs Institute's critical appraisal checklists for other study types, such as case–control and cohort studies, case series and case reports, will be used to assess methodological quality. Overall conclusions will reflect the quality and type of evidence included. This systematic review will represent the first comprehensive attempt to assess the value of homeopathic treatment in the management of hemorrhoids in an Indian population.
Gautam et al. (Wed,) studied this question.
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