Background: Ayurveda, as an ancient science of life, prioritises the maintenance of a healthy baseline state over mere disease management. This structural and functional health is governed by the Srotas (channel) system, which is highly prone to losing its metabolic integrity due to an erratic lifestyle and faulty dietary habits. Within this framework, the Raktavaha Srotas is responsible for transporting blood cells and haemoglobin to fulfil the vital functional role of Jeevana (the absolute sustenance of life). Aim the liver executes Ranjana Karma (coloration) by functioning as a warehouse storing iron, Vitamin B12, and folic acid, synthesizing transferrin, and secreting erythropoietin. Concurrently, the spleen provides crucial quality control and architectural refinement through cellular culling, iron recycling, and pitting. This physiological relationship is pathologically validated, as severe blood channel vitiation mirrors modern hemolytic states that manifest as Pleeha Vriddhi (splenomegaly). Conclusion: The classical designation of the liver and spleen as the Moolasthanas (roots) of the Raktavaha Srotas represents an advanced, holistic systems-biology model. It accurately captures the lifelong logistical, regulatory, and quality control architecture necessary to produce and sustain healthy blood tissue
Sharma et al. (Sun,) studied this question.