CDN-354 converts the CDN-352/353 uncertainty ledger into a measurement-design ladder. With the gate margin S = Theta - Tᵣequired (C, R) fixed, a covariance-shaped external fit becomes decisive only when |S|/sigmaS clears the chosen threshold. The strong anchor is already a 2-sigma closure under the independent moderate profile, but all-positive covariance requires a sharper score uncertainty to resolve the same cap vector. The locked result is DECISIVENESSISMARGINOVERERRORNOTLABEL.
Nicky Joseph Hubertus Catharina Hacquier (Thu,) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: