What question did this study set out to answer?

The aim is to extend the laminar biLayer model to a full 3D simulation of cortical fields on the fsaverage5 atlas.

July 1, 2026Open Access

CIFT-Geometry IV: Three-Dimensional Cortical Field Simulation on fsaverage5 — P8 Confirmed on Cortical Surface

Key Points

The aim is to extend the laminar biLayer model to a full 3D simulation of cortical fields on the fsaverage5 atlas.
Utilized a full 3D cortical surface simulation based on the fsaverage5 atlas with 10,242 vertices and 71,682 edges.
Developed an anatomical proxy for cortical architecture that is compatible with myelination gradients.
Validated the P8 regime on the cortical surface against neurodevelopmental conditions.
C1 values: NT=0.217, ASD=0.387, ADHD-c=0.592, SOC=0.707.
C2_local results: NT=0.027, ASD=0.098, ADHD-c=0.768, SOC=0.782.

Abstract

CIFT-Geometry IV extends the laminar biLayer model (Geometry III, DOI: 10. 5281/zenodo. 20783981) to a full 3D cortical surface simulation using the fsaverage5 atlas (10, 242 vertices, 71, 682 edges). The cortical field Φ (x) is modulated by an anatomical cortical architecture proxy compatible with myelination gradients Mᵢ (x) = thick (x) ⁻¹ + sulc (x). P8 is confirmed on cortical surface: NT is the unique regime with simultaneously low C1∩C2ₗocal. Results: C1: NT=0. 217, ASD=0. 387, ADHD-c=0. 592, SOC=0. 707. C2ₗocal: NT=0. 027, ASD=0. 098, ADHD-c=0. 768, SOC=0. 782. Related to: 10. 5281/zenodo. 20783981.

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