This study provides a comparative and critical review of major regional development theories through the lenses of globalization and innovation. Regional development is conceptualized as a multidimensional and territorially embedded process that extends beyond economic growth to include institutional capacity, human capital, governance structures, innovation capability, and spatial inequality. Since the 1970s, accelerating globalization has transformed the ways in which regions integrate into global production networks and value chains, making innovation a key mediating factor shaping regional competitiveness and adaptability. The paper examines growth pole theory, agglomeration and cluster approaches, endogenous growth and human capital theories, Krugman’s new economic geography, new regionalism, regional innovation systems and smart specialization approach within a unified analytical framework. While some of these approaches effectively explain spatial concentration, productivity gains, and competitiveness under globalization, they often underestimate issues related to social cohesion, institutional diversity, and uneven development. In particular, the highly abstract nature of new economic geography models limits their capacity to account for the social and institutional dimensions of regional development. The main finding of the study is that globalization and innovation do not produce automatic or uniform regional development outcomes. Instead, their effects are strongly mediated by regional institutional quality, innovation systems, and governance capacity. Accordingly, the paper argues that effective regional development policies should adopt a hybrid and region-based approach that balances competitiveness with inclusiveness and sustainability. Such an approach is especially relevant for countries characterized by pronounced regional disparities.
Sultan SARI (Tue,) studied this question.