Background: Indriyasthana is the fifth section of Charaka Samhita and comprises twelve chapters primarily devoted to prognosis (Arishta Lakshana). It equips physicians with methods to assess whether a disease is curable or incurable by observing alterations in the senses, complexion, voice, smell, dreams, mental state, and other clinical signs before initiating treatment. It is therefore considered one of the earliest systematic treatises on prognostic medicine. Objective: To review the importance of Indriyasthana and evaluate its contribution to Ayurvedic diagnosis, prognosis, clinical decision-making, and its relevance to contemporary medical practice. Materials and Methods: Classical Ayurvedic literature, especially Charaka Samhita with traditional commentaries, standard Ayurvedic textbooks, and published review articles on Indriyasthana were critically reviewed. Results: Indriyasthana provides a comprehensive framework for prognostic assessment through Arishta Lakshana, enabling physicians to identify terminal conditions, determine the likelihood of recovery, and plan treatment ethically and rationally. Conclusion: The principles of Indriyasthana continue to be clinically relevant for prognosis, critical care, palliative medicine, physician ethics, and evidence-based Ayurvedic practice.
Chaturvedi et al. (Thu,) studied this question.
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