Unravelling the paradox of smoking cessation in multimorbidity: the roles of polypharmacy and treatment burden

Key Points

• This research aims to explore how polypharmacy and treatment burden impact smoking cessation in individuals with multimorbidity.
• Literature review on smoking cessation and its relation to multimorbidity, polypharmacy, and treatment burden.
• Theoretical framework analysis to understand the interactions among identified components.
• Identified significant barriers related to polypharmacy that hinder smoking cessation efforts in patients with multiple health conditions.
• Suggested that higher treatment burden correlates with reduced likelihood of successful smoking cessation.